Dr. Lingbo Zhang’s Lab at Cold Spring Harbor Laboratory focuses on both basic science and translational medicine of hematologic malignancies. The research of the Lab centers on normal and malignant stem and progenitor cells in the hematopoietic system and decodes the role of metabolites, including micronutrients and neurotransmitters, in the tumor microenvironment and their genetic effectors in regulating hematologic malignancies.
There are two fully funded postdoctoral fellowships available to investigate the roles of these critical metabolites and their genetic effectors in hematopoietic malignancies and develop novel therapeutic strategies.
Position Responsibilities
The Lab utilizes a combination of CRISPR/Cas functional genomics and metabolomics as well as optogenetics and fiber photometry approaches to systematically uncover the critical metabolites and their genetic effectors, including receptors and metabolic enzymes, to reveal mechanistic insights of and identify key drug targets for hematologic malignancies. The ultimate goal is to understand how environmental signals such as diets and nervous system activities modulate blood cell development and cancers. Based on these basic mechanistic insights, the Lab is building innovative therapeutics to treat hematopoietic malignancies that are currently without effective therapeutic options.
Position Requirements
Education: Applicants should hold a PhD in biomedical sciences
Experience/Skills: Ideal candidates should have strong research backgrounds in molecular and cellular biology, animal model and cancer research, and experiences with flow cytometry and metabolomics analysis or optogenetics and fiber photometry..
Supplemental Information
How to Apply:
For immediate consideration please apply to the opening found here: Zhang Postdoctoral Fellow Position ID: 2152. Interested candidates should send cover letter, CV, research statement (including research accomplished during PhD and research expected to work on during postdoctoral fellowship), and 3 contacts for reference to lbzhang@cshl.edu.
Environment
Cold Spring Harbor Laboratory is a world-renowned biomedical research institution in New York. It has shaped contemporary biomedical research and is the home of eight Nobel Prize laureates. Cold Spring Harbor Laboratory provides a highly dynamic and interactive research environment and also a unique opportunity of timely exposure to advances in various biomedical research fields and of interaction with a broad range of researchers from all over the world through its renowned Meetings and Courses program. We believe that science is for everyone and our researchers have a wide variety of backgrounds.
Compensation and Benefits
Our employees are compensated in many ways for their contributions to our mission, including competitive pay, exceptional health benefits, retirement plans, paid time off, and a range of recognition and wellness programs. Visit our CSHL Benefits & Postdoctoral Landing sites to learn more. The salary for this role is $74,300.00 per annum. The salary range or hourly rate listed is a good faith determination of potential base compensation that may be offered to a successful applicant for this position at the time of this job advertisement and may be modified in the future. When determining a base salary and/or rate, several factors may be considered as applicable (e.g., years of relevant experience, education, credentials, and internal equity).
CSHL is an EO Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, or protected veteran status. VEVERAA Federal Contractor
